HCG STAT for cobas e 411: Immunoassay for the determination of hCG in serum and plasma

HCG is produced in the placenta during pregnancy and its role is to maintain the corpus luteum. It also influences steroid production. HCG exists as a number of isohormones and the serum of pregnant women contains mainly intact hCG.1–3 Measurement of hCG levels is used clinically to diagnose pregnancy as early as one week after conception. In addition, elevated hCG concentrations during the first trimester are indicative of chorionic carcinoma, hydatidiform mole, or multiple pregnancy, whereas decreased levels are associated with threatening or missed abortion, ectopic pregnancy, gestosis, or intra-uterine death.1–3